In addition, some genes seem like exclusively chosen at relapse. For instance, modest clones harboring TP53 mutations ordinarily grow and dominate the disorder right after CIT, which explains the poor prognosis associated with these subclonal mutations.12,sixty two Besides TP53, mutations in IKZF3 and SAMHD1 have also been recurrently selected in https://arthurviudm.bcbloggers.com/31614142/the-link-alternatif-mbl77-diaries