At present, there are two varieties of scientific tests on itaconate: Irg1−/− macrophages and the regulatory outcome of itaconate derivatives. These two success were complementary and disclosed the regulatory mechanisms of itaconate involved alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription component 3 (ATF3) induction to inhibit https://edmundx110juf3.blogsvirals.com/profile