In the long run, it relies on your travel itinerary as you can go to the jungle just before or soon after your tours in Cusco. From Lima to Iquitos you should have a lot more flights obtainable and possibly also much less expensive ones than from Cusco to Iquitos. https://peruamazontoursiquitos49260.blogaritma.com/26357140/the-best-side-of-peru-amazon-tours